1H-Indole-3-carboxaldehyde, 5-methyl- (9CI)
5-Methylindole-3-carboxaldehyde
CAS: 52562-50-2
Molecular Formula: C10H9NO
1H-Indole-3-carboxaldehyde, 5-methyl- (9CI) - Names and Identifiers
| Name | 5-Methylindole-3-carboxaldehyde |
| Synonyms | AKOS JY2082657 5-METHYLINDOLE-3-ALDEHYDE 5-METHYLINDOLE-3-CARBALDEHYDE 5-Methylindole-3-carboxaldehyde 5-METHYLINDOLE-3-CARBOXALDEHYDE 5-METHYLINDOLE-3-CARBOXYALDEHYDE 5-METHYL-1H-INDOLE-3-CARBALDEHYDE 1H-Indole-3-carboxaldehyde, 5-methyl- (9CI) |
| CAS | 52562-50-2 |
| InChI | InChI=1/C10H9NO/c1-7-2-3-10-9(4-7)8(6-12)5-11-10/h2-6,11H,1H3 |
1H-Indole-3-carboxaldehyde, 5-methyl- (9CI) - Physico-chemical Properties
| Molecular Formula | C10H9NO |
| Molar Mass | 159.18 |
| Density | 1.226±0.06 g/cm3(Predicted) |
| Melting Point | 148-151°C(lit.) |
| Boling Point | 348.2±22.0 °C(Predicted) |
| Flash Point | 172.3°C |
| Vapor Presure | 5.12E-05mmHg at 25°C |
| pKa | 15.68±0.30(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.698 |
1H-Indole-3-carboxaldehyde, 5-methyl- (9CI) - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| Hazard Class | IRRITANT |
1H-Indole-3-carboxaldehyde, 5-methyl- (9CI) - Introduction
It is also known as an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: It is a solid and can appear as colorless to light yellow crystals.
-Solubility: It is soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide, but hardly soluble in water.
Use:
-Chemical research: It can be used as a raw material for organic synthesis and for the synthesis of other compounds or drugs.
-Drug development: This compound has certain potential in the field of drug development and may be used to synthesize biologically active compounds.
Preparation Method:
It can be prepared by the following reaction:
1.5-methyl -1H-indole and oxidizing agent such as acidic potassium permanganate reaction, 5-methyl -1H-indol-3-ol.
2.5-methyl -1H-indole -3-ol and methyl iodide react to generate 5-methyl -1H-indole -3-methanol.
3. react 5-methyl -1H-indole-3-methanol with an alkaline solution such as sodium hydroxide to generate a phenol.
Safety Information:
-may be irritating to the eyes, skin and respiratory system, and protective measures should be taken when touching.
-When using or storing, keep away from fire and oxidizing agents, and maintain a well-ventilated environment.
-During the operation, care should be taken to avoid inhaling its powder or solution, and avoid contact with skin and eyes.
-In case of accidental contact, immediately flush the affected area with plenty of water and seek medical assistance.
Nature:
-Appearance: It is a solid and can appear as colorless to light yellow crystals.
-Solubility: It is soluble in organic solvents such as ethanol, chloroform and dimethyl sulfoxide, but hardly soluble in water.
Use:
-Chemical research: It can be used as a raw material for organic synthesis and for the synthesis of other compounds or drugs.
-Drug development: This compound has certain potential in the field of drug development and may be used to synthesize biologically active compounds.
Preparation Method:
It can be prepared by the following reaction:
1.5-methyl -1H-indole and oxidizing agent such as acidic potassium permanganate reaction, 5-methyl -1H-indol-3-ol.
2.5-methyl -1H-indole -3-ol and methyl iodide react to generate 5-methyl -1H-indole -3-methanol.
3. react 5-methyl -1H-indole-3-methanol with an alkaline solution such as sodium hydroxide to generate a phenol.
Safety Information:
-may be irritating to the eyes, skin and respiratory system, and protective measures should be taken when touching.
-When using or storing, keep away from fire and oxidizing agents, and maintain a well-ventilated environment.
-During the operation, care should be taken to avoid inhaling its powder or solution, and avoid contact with skin and eyes.
-In case of accidental contact, immediately flush the affected area with plenty of water and seek medical assistance.
Last Update：2024-04-09 02:00:46
